couple of tips.. (seeing im from the bloody place)
Escape is the biggest and best Venue i think. Chemistry (Marysol and Marcello) play on a regular basis, always a good night..
Powerzone is defin. a spot to check out, they play a lot of hard house. something u never hear over here.. Look for DJ tom Harding.. plays there quite a bit. Does a lot of HQ parties all over holland..
Panama is the most popular, if ure up for the big parties....
Best Coffeeshop in town is the Rokerj, right by the Leidseplen... not only for the product but also for the atmosphere..
as far as the red light district. go to the Banana Bar, 40 euros, drink free for an hour and see something most people havent even dreamt about.
www.id-t.com